The HIV pandemic has killed 36 million people since 1981. However, due to the nature of how it spreads, there has been little economic impact.
The flu pandemic of 1968 killed 1 million people.
The "asian flu" pandemic of 1956-1958 killed 2 million people.
Bank officials estimate that a "mild" pandemic, similar to the Hong Kong flu of 1968-69, could kill 1.4 million people and reduce global GDP by 0.7% in the first year, Bloomberg reported. Oct 17, 2008
That's POINT seven percent. Put another way, global GDP would still be at 99.3% of normal.
Of course, when they did those numbers I doubt they took into account the economics of "shelter in place". IE: They used figures of everybody still working.