Who is responsible for ISIS? Reagan, Bush, Clinton, Bush or Obama?

Mike Pence

Decades of the west meddling in the ME. 

Reagan, Bush, Clinton, Bush, Obama in that order, but the first four shoulder the majority of the responsibility

Ignorance and indoctrination.

Walt Disney, when he started that ride, "It's a small world".  Muslim's / Islam's got jealous and wanted their own State / Country.  But the real culprit was / is Lucifer.