Yes and no. I was on dating sites for a bit and, during that phase, "rejection" was totally ok. I was looking for a good match and if someone wasn't interested, it obviously wasn't them. Good to get them out of the way, so I could find the right one. Rejection once in a relationship is a different beast altogether, though.
I don't care one iota about that if nothing else is attached. I don't care what people think of me unless I need them for something. In other words I need people to like me at work, at school, at church even. But I don't care what anyone thinks that cannot use their greasy little fingers to do evil to me.