I am POA for my mother, who is in long term care facility. I make most decisions for her. Decisions that are less impactful to her situation I do ask her preference. I can't imagine being alive and having no say about anything to do with me.
I make all decisions for my elder daughter. She is physically and mentally handicapped. A few years ago, my younger daughter and I went to family court to make her a co-guardian of her sister, due to my age. But she lives with me and depends on me for everything, including decisions.