Depends on what it is....If it is something that shapes each person's value and actions probably not. But if it is something they can agree to disagree about that will not cause fights in other areas of life.
Thank you for your reply m2c. :) Like thee and me? Through a computer screen? How many years has it been including Answerbag? I honestly don't know. Do you? :)
Definitely depends what the matter of disagreement is.. there are many things I could live with if someone close didn't agree on.. but there are some fundamentals that I just couldn't live with.