Nope. Trump's besotted worshippers would vote for him even if he stabbed a pregnant woman in the middle of Times Square in broad daylight. And the "Never Trumpers" wouldn't vote for him even if his only opponent was Joseph Stalin. What this does do is smash the wedge that already existed between the GOP and the Democrats with a 20lb sledgehammer, there will be absolutely no room for bipartisanship now.
Four years of government inertia is always a bad thing. Nothing will be passed if the Dems continue to hold the Senate, as is likely. They picked up a seat at the midterms, which is almost unheard of during an economic downturn.